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Computational Models in Systems Biology: Standards, Dissemination, and Best Practices

L. Sordo Vieira,Reinhard C. Laubenbacher

2022 · DOI: 10.1016/j.copbio.2022.102702
Current Opinion in Biotechnology · 25 Citations

TLDR

This review covers existing standards, and it highlights the most important areas where further work is required, including the specification of agent-based models, an increasingly common modeling approach.

Abstract

Mathematical and computational models are a key technology in systems biology. Progress in the field depends on the replicability and reproducibility of their properties and behavior. For this, an essential requirement is a set of clear standards for model specification and dissemination. This review covers existing standards, and it highlights the most important areas where further work is required. This includes the specification of agent-based models, an increasingly common modeling approach.