Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD
Comparison of different MRI brain atrophy rate measures with clinical disease progression in AD
C. Jack,M. Shiung,9 Authors,R. Petersen
2004 · DOI: 10.1212/01.WNL.0000110315.26026.EF
Neurology · 854 Citations
TLDR
These data support the use of rates of change from serial MRI studies in addition to standard clinical/psychometric measures as surrogate markers of disease progression in AD, and atrophy on MRI was detected more consistently than decline on specific cognitive tests/rating scales.