Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer.
Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer.
Maha M. Saad,O. Garbuzenko,T. Minko
2008 · DOI: 10.2217/17435889.3.6.761
Nanomedicine · 345 Citations
TLDR
The NDS provides an effective co-delivery of DOX and siRNA as well as cell-death induction and suppression of cellular resistance in MDR lung cancer cells and demonstrates NDS-enhanced efficiency of chemotherapy to a level that cannot be achieved by applying its components separately.