Clearance of Citrobacter rodentium Requires B Cells but Not Secretory Immunoglobulin A (IgA) or IgM Antibodies
Clearance of Citrobacter rodentium Requires B Cells but Not Secretory Immunoglobulin A (IgA) or IgM Antibodies
C. Maaser,M. P. Housley,7 Authors,L. Eckmann
2004 · DOI: 10.1128/IAI.72.6.3315-3324.2004
Infection and Immunity · 223 Citations
TLDR
The results indicate that host defense against C. rodentium depends on B cells and IgG antibodies but does not require production or transepithelial transport of IgA or secreted IgM, and systemic administration of immune sera abrogated this effect.