Cigarette smoke-induced alterations in endothelial nitric oxide synthase phosphorylation: role of protein kinase C.
Cigarette smoke-induced alterations in endothelial nitric oxide synthase phosphorylation: role of protein kinase C.
L. Wagner,B. Laczy,8 Authors,I. Wittmann
2007 · DOI: 10.1080/10623320701606707
35 Citations
TLDR
The shift of the eNOS phosphorylation pattern to an inhibitory state seems to be independent of the PKA and phosphoinositol 3-kinase (PI3-K)/Akt pathways, whereas PKC appears to play a key role.