Chikungunya fever outbreak: Addressing globle public health challenge through One Health approaches

Since 2004, chikungunya fever (CHIKF), a neglected tropical disease, has emerged as a growing public health concern, with outbreaks reported in over 119 countries across Asia, Africa, the Americas, Europe, and Oceania. Currently, there is no specific antiviral treatment available for chikungunya virus (CHIKV) infection, highlighting an urgent need for innovative preventive strategies. In July 2025, an outbreak of CHIKF was reported in Foshan City, Guangdong Province, China, resulting in more than 7000 confirmed cases within a single month. This review aimed to examine the intricate interactions among etiology, epidemiological distribution, Aedes mosquito vectors, environmental factors (such as urbanization and climate change), and human behavioral patterns in disease transmission within the One Health framework, providing policymakers with actionable insights to bridge existing disciplinary gaps between human medicine, veterinary science, and environmental management in addressing the threat of arboviral diseases.