Cell mechanics control rapid transitions between blebs and lamellipodia during migration
Cell mechanics control rapid transitions between blebs and lamellipodia during migration
M. Bergert,S. D. Chandradoss,Ravi A. Desai,E. Paluch
2012 · DOI: 10.1073/pnas.1207968109
Proceedings of the National Academy of Sciences of the United States of America · 328 Citations
TLDR
The data reveal that the type of protrusion formed by migrating cells can be dynamically controlled independently of overall cell morphology, suggesting that protrusion formation is an autonomous module in the regulatory network that controls the plasticity of cell migration.