Brain morphological changes in hypokinetic dysarthria of Parkinson's disease and use of machine learning to predict severity
Brain morphological changes in hypokinetic dysarthria of Parkinson's disease and use of machine learning to predict severity
Yingchuan Chen,Guanyu Zhu,6 Authors,Jianguo Zhang
2020 · DOI: 10.1111/cns.13304
CNS Neuroscience & Therapeutics · 19 Citations
TLDR
Up to 90% of patients with Parkinson's disease eventually develop the speech and voice disorder referred to as hypokinetic dysarthria, and no reliable model for predicting the severity of HD based on neuroimaging has yet been developed.
Abstract
Up to 90% of patients with Parkinson's disease (PD) eventually develop the speech and voice disorder referred to as hypokinetic dysarthria (HD). However, the brain morphological changes associated with HD have not been investigated. Moreover, no reliable model for predicting the severity of HD based on neuroimaging has yet been developed.