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Brain dopamine and obesity

Gene-Jack Wang,N. Volkow,5 Authors,J. Fowler

2001 · DOI: 10.1016/S0140-6736(00)03643-6
The Lancet · 1,809 Citations

TLDR

Dopamine modulates motivation and reward circuits and hence dopamine deficiency in obese individuals may perpetuate pathological eating as a means to compensate for decreased activation of these circuits.