Binding mechanisms of TATA box-binding proteins: DNA kinking is stabilized by specific hydrogen bonds.
Binding mechanisms of TATA box-binding proteins: DNA kinking is stabilized by specific hydrogen bonds.
L. Pardo,M. Campillo,2 Authors,H. Weinstein
2000 · DOI: 10.1016/S0006-3495(00)76746-4
Biophysical Journal · 27 Citations
TLDR
A mechanism for the stabilization of DNA kinks is suggested, as the hydrogen bonds are found to contribute the energy necessary to drive the conformational transition at the central basepair step of TBP.