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Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology.

G. Hajishengallis,Richard J. Lamont

2012 · DOI: 10.1111/j.2041-1014.2012.00663.x
Molecular Oral Microbiology · 1,069 Citations

TLDR

A new model of pathogenesis according to which periodontitis is initiated by a synergistic and dysbiotic microbial community rather than by select 'periopathogens', such as the 'red complex' is described.