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Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

Fiona M Menzies,Angeleen Fleming,19 Authors,D. Rubinsztein

2017 · DOI: 10.1016/j.neuron.2017.01.022
Neuron · 929 Citations

TLDR

How autophagy upregulation may be a therapeutic strategy in a wide range of neurodegenerative conditions is described and possible pathways and druggable targets that may be suitable for this objective are considered.

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