Antimicrobial peptides: general overview and clinical implications in human health and disease.
Antimicrobial peptides: general overview and clinical implications in human health and disease.
Eduardo Guaní-Guerra,T. Santos-Mendoza,S. Lugo-Reyes,L. Teran
2010 · DOI: 10.1016/j.clim.2009.12.004
Clinical Immunology · 562 Citations
TLDR
This review focuses on cathelicin and defensins, the most documented human AMPs, and discusses their antimicrobial activity and pleiotropic immunomodulating effects on inflammatory and infectious diseases.