Antifactor Xa levels vs. activated partial thromboplastin time for monitoring unfractionated heparin. A pilot study
Antifactor Xa levels vs. activated partial thromboplastin time for monitoring unfractionated heparin. A pilot study
Sophie Samuel,T. Allison,6 Authors,HUIMAHN A. Choi
TLDR
This study compared the performance of an aPTT protocol vs. an anti‐Xa protocol in adult patients as defined by the time to reach therapeutic range, the percentage of time the values were within the goal range and the number of times laboratory monitoring was conducted.
Abstract
The two most common methods for monitoring unfractionated heparin (UFH) infusion are the activated partial thromboplastin time (aPTT) and the antifactor Xa heparin assay (anti‐Xa). The purpose of this study is to compare the performance of an aPTT protocol vs. an anti‐Xa protocol in adult patients as defined by the time to reach therapeutic range, the percentage of time the values were within the goal range and the number of times laboratory monitoring was conducted. We then analysed the discordance between paired values of anti‐Xa and aPTT.