Antibiotic Education: Not Just Another Brick in the Cell Wall.
Antibiotic Education: Not Just Another Brick in the Cell Wall.
Inka Sastalla,Sandip K. Datta
2015 · DOI: 10.1016/j.chom.2015.10.019
Cell Host and Microbe · 2 Citations
TLDR
It is shown that β-lactam treatment of MRSA leads to synthesis of an altered cell wall that increases inflammasome activation and immunopathology during skin infection.
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) are resistant to β-lactam antibiotics, which inhibit bacterial cell wall synthesis. In this issue of Cell Host & Microbe, Müller et al. (2015) show that β-lactam treatment of MRSA leads to synthesis of an altered cell wall that increases inflammasome activation and immunopathology during skin infection.