Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor.
Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor.
Hyun Ju Lee,S. Chattopadhyay,2 Authors,Keesook Lee
2003 · DOI: 10.1093/TOXSCI/KFG150
Toxicological Sciences · 444 Citations
TLDR
The results suggest that BPA and NP affect multiple steps of the activation and function of AR, thereby inhibiting the binding of native androgens to AR, AR nuclear localization, AR interaction with its coregulator, and its subsequent transactivation.