Analysis of Loci Required for Determination of Serotype Antigenicity in Streptococcus mutans and Its Clinical Utilization

The genes responsible for the serotype c-specific glucose side chain formation of rhamnose-glucose polysaccharide (RGP) in Streptococcus mutans were located downstream from the rgpA through rgpF locus that is involved in the synthesis of RGP, suggesting that these regions participated in serotype- specific glucose sidechain formation in each serotype strain.