An Improved Synthesis of Rimonabant: Anti-Obesity Drug#
An Improved Synthesis of Rimonabant: Anti-Obesity Drug#
Vijay Kumar Kotagiri,Sashikanth Suthrapu,4 Authors,R. Bandichhor
2007 · DOI: 10.1021/OP700110B
34 Citations
TLDR
A novel, cost-effective, and efficient process was developed for the large-scale synthesis of Rimonabant 1, an anti-obesity drug, using the conversion of 4-chloro propiophenone 2 to cyclized acid 6 as a key intermediate.