Amphiphilic hyper-branched co-polymer nanoparticles for the controlled delivery of anti-tumor agents.
Amphiphilic hyper-branched co-polymer nanoparticles for the controlled delivery of anti-tumor agents.
Qinghua Miao,Dongxue Xu,8 Authors,Yuliang Zhao
2010 · DOI: 10.1016/j.biomaterials.2010.06.012
Biomaterials · 44 Citations
TLDR
An amphiphilic co-polymer with hyper-branched poly(amine-ester) and polylactide and HPAE-co-PLA is designed and synthesized to generate nanoparticles (NPs) and direct microscopic observation revealed that the fluorescent NPs were taken up by cells and localized, in part, in organelles consistent with lysosomes.