Alternative Strategies in Thalassemia: Focus on Thalidomide
Alternative Strategies in Thalassemia: Focus on Thalidomide
R. Naithani,P. Jeyaraman,M. Mahapatra
2020 · DOI: 10.1007/s12288-020-01285-w
Indian Journal of Hematology and Blood Transfusion · 2 Citations
TLDR
Thalidomide has been shown to increase hemoglobin F levels through inducing c-globin mRNA expression in a dose-dependent manner by increasing intracellular reactive oxygen species and is known for its immune-modulating and anti-angiogenic properties.