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A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment

Xiangyang Wu,S. Cobbina,3 Authors,Liuqing Yang

2016 · DOI: 10.1007/s11356-016-6333-x
Environmental science and pollution research international · 887 Citations

TLDR

In this review, the major mechanism associated with toxicities of individual metals was the generation of reactive oxygen species (ROS), and toxicities were expressed through depletion of glutathione and bonding to sulfhydryl groups of proteins.