A Physiologically Based Approach To the Study of Bisphenol a and Other Estrogenic Chemicals On the Size of Reproductive Organs, Daily Sperm Production, and Behavior
A Physiologically Based Approach To the Study of Bisphenol a and Other Estrogenic Chemicals On the Size of Reproductive Organs, Daily Sperm Production, and Behavior
F. V. vom Saal,P. Cooke,5 Authors,W. Welshons
1998 · DOI: 10.1177/074823379801400115
Toxicology and industrial health · 805 Citations
TLDR
Two chemicals previously shown to have estrogenic activity, bisphenol A and octylphenol, were examined for their effects on accessory reproductive organs and daily sperm production in male offspring of mice fed these chemicals during pregnancy and it was found that the 2 ng/g dose permanently increased the size of the preputial glands, but reduced thesize of the epididymides.