A novel synthetic mammalian promoter derived from an internal ribosome entry site.
A novel synthetic mammalian promoter derived from an internal ribosome entry site.
Shizuka Hartenbach,M. Fussenegger
2006 · DOI: 10.1002/BIT.21174
Biotechnology and Bioengineering · 11 Citations
TLDR
This novel synthetic P(GTX) promoter exhibited consensus core promoter modules such as the initiator and the partial downstream promoter elements (DPE) and mediated high-level expression of a variety of transgenes including the human vascular endothelial growth factor 121 (VEGF(121).