A Multidomain Fusion Protein in Listeria monocytogenes Catalyzes the Two Primary Activities for Glutathione Biosynthesis
A Multidomain Fusion Protein in Listeria monocytogenes Catalyzes the Two Primary Activities for Glutathione Biosynthesis
S. Gopal,I. Borovok,5 Authors,Y. Aharonowitz
2005 · DOI: 10.1128/JB.187.11.3839-3847.2005
Journal of Bacteriology · 100 Citations
TLDR
It is demonstrated that Listeria monocytogenes contains a novel multidomain protein (termed GshF) that carries out complete synthesis of glutathione, the predominant low-molecular-weight peptide thiol present in living organisms and a key role in protecting cells against oxygen toxicity.