A FAS-ligand variant associated with autoimmune lymphoproliferative syndrome in cats
A FAS-ligand variant associated with autoimmune lymphoproliferative syndrome in cats
D. Aberdein,J. Munday,25 Authors,Wesley C. Warren
2016 · DOI: 10.1007/s00335-016-9668-1
Mammalian Genome · 15 Citations
TLDR
Identification of a genetic defect in the FAS-mediated apoptosis pathway confirms that the lymphoproliferative disease in BSH cats fulfills the diagnostic criteria for ALPS in humans.