A Computational Hypothesis on How Serotonin Regulates Catecholamines in the Pathogenesis of Depressive Apathy
A Computational Hypothesis on How Serotonin Regulates Catecholamines in the Pathogenesis of Depressive Apathy
Massimo Stefano Silvetti,G. Baldassarre,Daniele Caligiore
2019 · DOI: 10.1007/978-3-030-18830-6_12
5 Citations
TLDR
A hypothesis is proposed based on a computational model for which some depressive features may be produced by pathologically low levels of serotonin, which in turn causes a downregulation of catecholamine release, which may be critical to the genesis of apathy.