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WNK4 phosphorylates ser206 of claudin‐7 and promotes paracellular Cl− permeability

Rodney Tatum,Yuguo Zhang,3 Authors,Yan-hua Chen

2007 · DOI: 10.1016/j.febslet.2007.07.014
FEBS Letters · 60 Citations

TLDR

TJ protein claudin‐7 and WNK4 were partially co‐localized in renal tubules of rat kidney and co‐immunoprecipitated in kidney epithelial cells and significantly increased paracellular permeability to Cl−.