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Vitamin D and survival in COVID-19 patients: A quasi-experimental study

C. Annweiler,B. Hanotte,3 Authors,T. Celarier

2020 · DOI: 10.1016/j.jsbmb.2020.105771
Journal of Steroid Biochemistry and Molecular Biology · 189 Citations

TLDR

Bolus vitamin D3 supplementation during or just before COVID-19 was associated with less severe COVID-19 in frail elderly and vitamin D3 supplementation during or just before COVID-19 was associated with better survival rate in frail elderly.

Abstract

Highlights • Vitamin D may be a central biological determinant of COVID-19 outcomes.• Bolus vitamin D3 supplementation during or just before COVID-19 was associated with less severe COVID-19 in frail elderly.• Bolus vitamin D3 supplementation during or just before COVID-19 was associated with better survival rate in frail elderly.• Randomized controlled trials are expected to firmly conclude the effect of vitamin D supplementation on COVID-19 prognosis.