UBE2D2 promotes gastric cancer progression by inhibiting ferroptosis through autophagy-dependent stabilization of CST1.
UBE2D2 promotes gastric cancer progression by inhibiting ferroptosis through autophagy-dependent stabilization of CST1.
Yanzhen Yang,Jingli Xu,6 Authors,Cong Luo
2025 · DOI: 10.1016/j.ijbiomac.2025.147333
International Journal of Biological Macromolecules · 0 Citations
TLDR
Findings indicate that UBE2D2 acts as an oncogene in GC by inhibiting ferroptosis through CST1 stabilization, suggesting a promising therapeutic strategy for GCPM.