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Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

R. Sperling,P. Aisen,18 Authors,C. Phelps

2011 · DOI: 10.1016/j.jalz.2011.03.003
Alzheimer's & Dementia · 6,545 Citations

TLDR

A conceptual framework and operational research criteria are proposed, based on the prevailing scientific evidence to date, to test and refine these models with longitudinal clinical research studies and it is hoped that these recommendations will provide a common rubric to advance the study of preclinical AD.