The type‐I interferon response potentiates seeded tau aggregation and exacerbates tau pathology
The type‐I interferon response potentiates seeded tau aggregation and exacerbates tau pathology
Sophie Sanford,Lauren V. C. Miller,7 Authors,W. McEwan
2023 · DOI: 10.1002/alz.13493
Alzheimer's & Dementia · 23 Citations
Abstract
Signatures of a type‐I interferon (IFN‐I) response are observed in the post mortem brain in Alzheimer's disease (AD) and other tauopathies. However, the effect of the IFN‐I response on pathological tau accumulation remains unclear.