The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
M. Johansson,M. Phillipson,3 Authors,G. Hansson
2008 · DOI: 10.1073/pnas.0803124105
Proceedings of the National Academy of Sciences of the United States of America · 2,143 Citations
TLDR
Findings show that the Muc2 mucin can build a mucus barrier that separates bacteria from the colon epithelia and suggest that defects in this mucus can cause colon inflammation.