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The increased mucosal mRNA expressions of complement C3 and interleukin‐17 in inflammatory bowel disease

T. Sugihara,T. Sugihara,6 Authors,A. Andoh

2010 · DOI: 10.1111/j.1365-2249.2010.04093.x
Clinical and Experimental Immunology · 128 Citations

TLDR

C3 and IL‐17 mRNA expressions are enhanced, with a strong correlation, in the inflamed mucosa of IBD patients, and part of these clinical findings was considered to be mediated by the colonic SEMF response to IL‐ 17.