The ever-expanding function of NOD2: autophagy, viral recognition, and T cell activation.
The ever-expanding function of NOD2: autophagy, viral recognition, and T cell activation.
Michael H. Shaw,N. Kamada,2 Authors,G. Núñez
2011 · DOI: 10.1016/j.it.2010.12.007
Trends in immunology · 84 Citations
TLDR
Recent studies have extended the biological activity of NOD2 to include the induction of autophagy and antiviral responses, as well as mediating direct T cell activation in the context of immune activation and pathogen detection.