The GA4GH Phenopacket schema defines a computable representation of clinical data
The GA4GH Phenopacket schema defines a computable representation of clinical data
Julius O. B. Jacobsen,M. Baudis,48 Authors,Peter N. Robinson
TLDR
This work aims to demonstrate the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals, not necessarily belonging to the same breeds.
Abstract
References 1. Dolgin, E. Nature 551, 427–431 (2017). 2. Haynes, W. A., Tomczak, A. & Khatri, P. Sci. Rep. 8, 1362 (2018). 3. Wood, V. et al. Open Biol. 9, 180241 (2019). 4. Stoger, T., Gerlach, M., Morimoto, R. I. & Nunes Amaral, L. A. PloS Biol. 16, e2006643 (2018). 5. Edwards, A. M. et al. Nature 470, 163–165 (2011). 6. Oprea, T. I. et al. Nat. Rev. Drug Discov. 17, 317–332 (2018). 7. Dunham, I. PLoS Biol. 16, e3000034 (2018). 8. Stoeger, T. & Nunes Amaral, L. A. eLife 9, e61981 (2020). 9. Hutchison, C. A. III et al. Science 351, aad6253 (2016). 10. Kustatscher, G. Nat. Methods https://doi.org/10.1038/s41592-02201454-x (2022). 11. Sinha, S., Eisenhaber, B., Jensen, L. J., Kalbuaji, B. & Eisenhaber, F. Proteomics 18, e1800093 (2018). 12. UniProt Consortium. Nucleic Acids Res. 47, D506–D515 (2019). 13. Anton, B. P. et al. PLoS Biol. 11, e1001638 (2013). 14. Gerlt, J. A. et al. Biochemistry 50, 9950–9962 (2011). 15. Williamson, A. R. Nat. Struct. Biol. 7, 953 (2000). 16. Koscielny, G. et al. Nucleic Acids Res. 45, D985–D994 (2017). Competing interests T.G. is a shareholder of Westlake Omics Inc. T.I. is a cofounder of Data4Cure, is on the Scientific Advisory Board and has an equity interest. T.I. is on the Scientific Advisory Board of Ideaya BioSciences and has an equity interest. E.L. is advisor for Pixelgen technologies and Moleculent. E.M.M. is a cofounder, shareholder and scientific board member of Erisyon, Inc. G.K., T.C., A.-C.G., H.H., K.S.L., M.R. and J.R. declare no competing interests.