The 28-day exposure to fenpropathrin decreases locomotor activity and reduces activity of antioxidant enzymes in mice brains
The 28-day exposure to fenpropathrin decreases locomotor activity and reduces activity of antioxidant enzymes in mice brains
B. Nieradko-Iwanicka,A. Borzęcki
2016 · DOI: 10.1016/j.pharep.2015.12.002
Pharmacological Reports · 12 Citations
TLDR
The decrease of SOD activity in mice brains results from direct inhibition of the enzyme by Fen and/or increased utilization due to excessive free radical formation in conditions of Fen-induced oxidative stress.