Targeting Sirtuin-1 in Huntington’s Disease: Rationale and Current Status
Targeting Sirtuin-1 in Huntington’s Disease: Rationale and Current Status
W. Duan
2013 · DOI: 10.1007/s40263-013-0055-0
CNS Drugs · 44 Citations
TLDR
Recent progress in SIRT1 research is summarized, with a focus on the specificity of this protein as a potential therapeutic target for HD, as well as existing challenges for developing Sirtuin-1 modulators for clinical use.