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TSG-6 Is Concentrated in the Extracellular Matrix of Mouse Cumulus Oocyte Complexes Through Hyaluronan and Inter-Alpha-Inhibitor Binding1

O. Carrette,Rashmi V. Nemade,2 Authors,W. J. Larsen

2001 · DOI: 10.1095/biolreprod65.1.301
Biology of Reproduction · 104 Citations

TLDR

Results suggest that TSG-6 has a structural role in COC matrix formation possibly mediating cross-linking of separate HA molecules through its binding to IαI, which is critical in organizing and stabilizing this matrix.