TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis
TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis
L. Ye,Sandra Kleiner,16 Authors,B. Spiegelman
2012 · DOI: 10.1016/j.cell.2012.08.034
Cell · 317 Citations
TLDR
The role of TRPV4 as a cell-autonomous mediator for both the thermogenic and proinflammatory programs in adipocytes could offer a target for treating obesity and related metabolic diseases.