Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages.
Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages.
M. Aursnes,J. Tungen,4 Authors,T. Hansen
2015 · DOI: 10.1021/acs.jnatprod.5b00574
Journal of Natural Products · 39 Citations
TLDR
Support is presented for the apprehended biosynthesis of 1 in human macrophages occurring via the intermediate 16S,17S-epoxyprotectin (5), based on results from LC/MS-MS metabololipidomics.