Substrate stiffness regulates temporary NF-κB activation via actomyosin contractions.
Substrate stiffness regulates temporary NF-κB activation via actomyosin contractions.
S. Ishihara,M. Yasuda,3 Authors,H. Haga
2013 · DOI: 10.1016/j.yexcr.2013.09.018
Experimental Cell Research · 74 Citations
TLDR
It is suggested that substrate stiffness regulates NF-κB activity via actomyosin contractions, resulting in morphological changes in cells grown on the soft substrate and on the stiff substrate, respectively.