Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3).
Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3).
W. Chung,B. Heddi,2 Authors,A. Phan
2014 · DOI: 10.1002/anie.201308063
183 Citations
TLDR
NMR spectroscopy revealed that Phen-DC3 interacts with the quadruplex through extensive π-stacking with guanine bases of the top G-tetrad.