Role of nrf2 in oxidative stress and toxicity.
Role of nrf2 in oxidative stress and toxicity.
Q. Ma
2013 · DOI: 10.1146/annurev-pharmtox-011112-140320
Annual Review of Pharmacology and Toxicology · 4,375 Citations
TLDR
The nuclear factor erythroid 2-related factor 2 (Nrf2) is an emerging regulator of cellular resistance to oxidants that controls the basal and induced expression of an array of antioxidant response element-dependent genes to regulate the physiological and pathophysiological outcomes of oxidant exposure.