Resveratrol inhibits the expression of SREBP1 in cell model of steatosis via Sirt1-FOXO1 signaling pathway.
Resveratrol inhibits the expression of SREBP1 in cell model of steatosis via Sirt1-FOXO1 signaling pathway.
Guang-Li Wang,Yu-cai Fu,3 Authors,Xiao-hui Zhou
2009 · DOI: 10.1016/j.bbrc.2009.01.163
Biochemical and Biophysical Research Communications - BBRC · 139 Citations
TLDR
The results suggest that resveratrol may attenuate fat deposition by inhibiting SREBP1 expression via Sirt1-FOXO1 pathway and thus may have application for the treatment of NAFLD.