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Resident Enteric Bacteria Are Necessary for Development of Spontaneous Colitis and Immune System Activation in Interleukin-10-Deficient Mice

Rance K. Sellon,S. Tonkonogy,5 Authors,R. Sartor

1998 · DOI: 10.1128/IAI.66.11.5224-5231.1998
Infection and Immunity · 1,559 Citations

TLDR

It is concluded that resident enteric bacteria are necessary for the development of spontaneous colitis and immune system activation in IL-10-deficient mice.