Regulation of SIRT1 in cellular functions: role of polyphenols.
Regulation of SIRT1 in cellular functions: role of polyphenols.
Sangwoon Chung,H. Yao,3 Authors,I. Rahman
2010 · DOI: 10.1016/j.abb.2010.05.003
Archives of Biochemistry and Biophysics · 656 Citations
TLDR
Activation of SIRT1 by polyphenols is beneficial for regulation of calorie restriction, oxidative stress, inflammation, cellular senescence, autophagy/apoptosis, autoimmunity, metabolism, adipogenesis, circadian rhythm, skeletal muscle function, mitochondria biogenesis and endothelial dysfunction.