Quality of TCR signaling determined by differential affinities of enhancers for the composite BATF–IRF4 transcription factor complex
Quality of TCR signaling determined by differential affinities of enhancers for the composite BATF–IRF4 transcription factor complex
A. Iwata,V. Durai,6 Authors,K. Murphy
2017
42 Citations
TLDR
A previously unknown high-affinity AICE2 motif at a human single-nucleotide polymorphism of the gene encoding the immunomodulatory receptor CTLA-4 that was associated with resistance to autoimmunity was identified.