Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.
Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.
M. Johansson,K. Thomsson,G. Hansson
2009 · DOI: 10.1021/pr9002504
Journal of Proteome Research · 234 Citations
TLDR
The protein composition of these two mucus layers from the mouse colon is analyzed and the Fcgbp protein is probably cleaved at GD/PH and covalently attached to Muc2 via one or several of its von Willebrand D domains.