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Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.

Dingzhi Wang,L. Fu,2 Authors,R. Dubois

2015 · DOI: 10.1053/j.gastro.2015.07.064
Gastroenterology · 259 Citations

TLDR

The PGE2 signaling pathway might be targeted therapeutically to slow CSC expansion and colorectal cancer progression and correlated with colonic CSC markers in human coloreCTal carcinoma samples.