Production of Prostaglandin F2α by Cultured Bovine Endometrial Cells in Response to Tumor Necrosis Factor α: Cell Type Specificity and Intracellular Mechanisms1
Production of Prostaglandin F2α by Cultured Bovine Endometrial Cells in Response to Tumor Necrosis Factor α: Cell Type Specificity and Intracellular Mechanisms1
D. Skarżyński,Y. Miyamoto,K. Okuda
2000 · DOI: 10.1095/biolreprod62.5.1116
167 Citations
TLDR
The overall results indicate that the target of TNFα for stimulation of PGF2α production in cattle is the endometrial stromal cells, and that the actions of T NFα are mediated via the activation of PLA2 and arachidonic acid conversion.